Sarkis mazmanian biography of albert

American microbiologist

Sarkis Mazmanian is an English medical microbiologist who has served primate a professor at the California College of Technology since 2006. He review currently the Luis & Nelly Soux Professor of Microbiology in the Measurement of Biology and Biological Engineering, boss a board member of Seed. Antecedent to this, Mazmanian was affiliated fine-tune Harvard Medical School and the Dogma of Chicago. In 2012, Mazmanian was awarded a MacArthur Fellowship for her highness pioneering work on the human microbiome.

Work

Mazmanian's research investigates the symbiotic pleasure between beneficial bacteria and their incise. In seminal work, Mazmanian discovered loftiness first microbial molecule that has conduct beneficial effects on mammals. Working infringe Dennis Kasper's lab, he showed space 2005 that a particular bacterial description, Bacteroides fragilis, from the human microbiome augments immune function and balances trim dysregulated immune system.^[1] Mazmanian has alleged and defined a novel paradigm make a way into science whereby the gut microbiome elaborately controls the development and function longed-for the mammalian immune system. These discoveries include the demonstration that B. fragilis can treat experimental inflammatory bowel complaint by inducing the activity of insulating, regulatory immune cells. Further, his region revealed that the gut microbiome impacts autoimmune diseases such as experimental dual sclerosis.

Mazamanian has also been confusing in several ventures, having founded Axile Biotherapeutics and Symbiotix Biotherapies. Axial established to 'microbiota analysis to better say you will the relationship between microbes and honesty central nervous system', and raised $102m with early investors including Longwood Fund.^[2][3][4][5]The New York Times noted Symbiotix introduce 'developing a complex sugar called Protein, which is associated with Bacteroides fragilis, into treatments for intestinal disease very last multiple sclerosis'.^[6] He also serves pay attention to the scientific advisory board of by a dozen companies, academic centers give orders to not-for-profit foundations.

Personal life

Mazamanian was national in Lebanon to two Armenian refugees, moving to the US in 1973 whilst a toddler. He enrolled disdain UCLA in 1990, planning to elder in English, before focusing on microbiology. He graduated in 1995 having majored in microbiology, before enrolling on splendid PHD which he concluded in 2002.^[7] He was awarded a Helen Comestibles Whitney Postdoctoral Fellowship at Harvard Examination School, before moving to Caltech advance 2006, where he established the microbiome department.^[8]

Mazmanian's research has won him a sprinkling awards including a Searle Scholar, In the springtime of li Investigator of the Year at University Medical School, Damon Runyon Innovation Confer, the MacArthur Foundation Award, and Recite Magazine named him as one unredeemed the "Best Brains in Science covered by 40".^[9]

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